Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Yadier Molina | Andrew Knizner | ||||
| First Base | Paul Goldschmidt | |||||
| Second Base | Matt Carpenter | Tommy Edman | ||||
| Shortstop | Paul DeJong | Edmundo Sosa | ||||
| Third Base | Nolan Arenado | |||||
| Left Field | Tyler O'Neill | |||||
| Center Field | Harrison Bader | José Rondón | ||||
| Right Field | Dylan Carlson | |||||
| Starting Pitcher | Adam Wainwright | Johan Oviedo | Wade LeBlanc | Carlos Martínez | Kwang Hyun Kim | |
| Closer | Alex Reyes | |||||
| Relief Pitcher | Giovanny Gallegos | Génesis Cabrera | Ryan Helsley | Andrew Miller | John Gant | Junior Fernández |
© 2021 by STATS PERFORM.Any commercial use or distribution without the express written consent of STATS PERFORM is strictly prohibited.