Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Tucker Barnhart | Juan Graterol | ||||
| First Base | Joey Votto | Derek Dietrich | ||||
| Second Base | Freddy Galvis | Alex Blandino | ||||
| Shortstop | José Iglesias | José Peraza | ||||
| Third Base | Eugenio Suárez | Josh VanMeter | ||||
| Left Field | Phillip Ervin | |||||
| Center Field | Nick Senzel | Brian O'Grady | ||||
| Right Field | Aristides Aquino | |||||
| Starting Pitcher | Luis Castillo | Trevor Bauer | Sonny Gray | Anthony DeSclafani | Tyler Mahle | |
| Closer | Raisel Iglesias | |||||
| Relief Pitcher | Robert Stephenson | Michael Lorenzen | Sal Romano | Amir Garrett | Kevin Gausman | Lucas Sims |
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