Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Tyler Stephenson | Luke Maile | ||||
| First Base | Joey Votto | |||||
| Second Base | Jonathan India | Alejo Lopez | ||||
| Shortstop | Kevin Newman | Jose Barrero | ||||
| Third Base | Spencer Steer | |||||
| Left Field | TJ Friedl | Stuart Fairchild | ||||
| Center Field | Nick Senzel | Michael Siani | ||||
| Right Field | Wil Myers | Nick Solak | ||||
| Starting Pitcher | Nick Lodolo | Hunter Greene | Luis Cessa | Graham Ashcraft | Justin Dunn | Luke Weaver |
| Closer | Alexis Díaz | |||||
| Relief Pitcher | Lucas Sims | Tejay Antone | Joel Kuhnel | Reiver Sanmartin | Ian Gibaut | Tony Santillan |
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