Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Danny Jansen | Alejandro Kirk | ||||
| First Base | Vladimir Guerrero Jr. | Reese McGuire | ||||
| Second Base | Marcus Semien | Jake Lamb | ||||
| Shortstop | Bo Bichette | |||||
| Third Base | Kevin Smith | |||||
| Left Field | Lourdes Gurriel Jr. | Jarrod Dyson | ||||
| Center Field | Teoscar Hernández | Randal Grichuk | ||||
| Right Field | Randal Grichuk | Breyvic Valera | ||||
| Designated Hitter | George Springer | |||||
| Starting Pitcher | Hyun Jin Ryu | Robbie Ray | José Berríos | Steven Matz | Alek Manoah | |
| Closer | Jordan Romano | |||||
| Relief Pitcher | Adam Cimber | Trevor Richards | Tim Mayza | Joakim Soria | Bryan Baker | Tayler Saucedo |
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