Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Cam Gallagher | Meibrys Viloria | ||||
| First Base | Cheslor Cuthbert | Lucas Duda | ||||
| Second Base | Nicky Lopez | |||||
| Shortstop | Adalberto Mondesi | |||||
| Third Base | Hunter Dozier | |||||
| Left Field | Alex Gordon | |||||
| Center Field | Bubba Starling | Billy Hamilton | ||||
| Right Field | Whit Merrifield | |||||
| Designated Hitter | Jorge Soler | |||||
| Starting Pitcher | Brad Keller | Jakob Junis | Glenn Sparkman | Danny Duffy | Mike Montgomery | |
| Closer | Ian Kennedy | |||||
| Relief Pitcher | Wily Peralta | Jake Diekman | Jorge López | Brian Flynn | Jake Newberry | Kevin McCarthy |
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