Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Yasmani Grandal | Seby Zavala | ||||
| First Base | José Abreu | Zack Collins | ||||
| Second Base | Leury García | Romy Gonzalez | ||||
| Shortstop | Tim Anderson | Danny Mendick | ||||
| Third Base | Yoán Moncada | Jake Burger | ||||
| Left Field | Eloy Jiménez | Micker Adolfo | ||||
| Center Field | Luis Robert | |||||
| Right Field | Adam Engel | Andrew Vaughn | ||||
| Designated Hitter | Gavin Sheets | Yermín Mercedes | ||||
| Starting Pitcher | Lucas Giolito | Lance Lynn | Dylan Cease | Dallas Keuchel | Michael Kopech | Reynaldo López |
| Closer | Liam Hendriks | |||||
| Relief Pitcher | Craig Kimbrel | Kendall Graveman | Aaron Bummer | Garrett Crochet | Ryan Burr | José Ruiz |
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