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Regular Season
| Pitching Statistics | |||||||||||||||||
| Year | Team | W | L | Sv-Op | G | GS | CG | IP | H | R | ER | HR | BB | IBB | K | WHIP | ERA |
| 2011 | Ari | 1 | 0 | 0 - 0 | 33 | 0 | 0 | 28.1 | 30 | 9 | 8 | 2 | 8 | 1 | 24 | 1.34 | 2.54 |
| 2012 | Ari | 1 | 6 | 2 - 4 | 64 | 0 | 0 | 59.1 | 60 | 29 | 23 | 4 | 24 | 3 | 41 | 1.42 | 3.49 |
| 2013 | Cle | 7 | 3 | 1 - 5 | 70 | 0 | 0 | 75.0 | 60 | 31 | 27 | 4 | 28 | 2 | 73 | 1.17 | 3.24 |
| 2014 | Cle | 5 | 5 | 2 - 9 | 80 | 0 | 0 | 76.1 | 61 | 26 | 22 | 6 | 22 | 4 | 64 | 1.09 | 2.59 |
| 2015 | Cle | 3 | 3 | 2 - 6 | 74 | 0 | 0 | 64.0 | 59 | 24 | 21 | 8 | 19 | 1 | 54 | 1.22 | 2.95 |
| 2016 | Cle | 2 | 5 | 1 - 4 | 75 | 0 | 0 | 66.2 | 56 | 26 | 24 | 8 | 28 | 3 | 69 | 1.26 | 3.24 |
| 2017 | Cle | 4 | 6 | 3 - 6 | 79 | 0 | 0 | 76.2 | 71 | 36 | 30 | 5 | 22 | 3 | 73 | 1.21 | 3.52 |
| 2018 | Col | 4 | 6 | 0 - 5 | 61 | 0 | 0 | 54.2 | 70 | 43 | 36 | 9 | 28 | 1 | 54 | 1.79 | 5.93 |
| 2019 | Col | 3 | 2 | 1 - 6 | 70 | 0 | 0 | 72.0 | 69 | 44 | 43 | 12 | 29 | 1 | 58 | 1.36 | 5.38 |
| 2020 | Sea | 1 | 0 | 0 - 1 | 6 | 0 | 0 | 6.0 | 13 | 12 | 12 | 1 | 6 | 0 | 4 | 3.17 | 18.00 |
| 2021 | Cle | 6 | 7 | 2 - 8 | 81 | 0 | 0 | 77.1 | 69 | 33 | 30 | 10 | 38 | 0 | 71 | 1.38 | 3.49 |
| 2022 | Cle | 6 | 2 | 1 - 1 | 60 | 2 | 0 | 58.1 | 58 | 38 | 35 | 9 | 26 | 1 | 52 | 1.44 | 5.40 |
| Career | 43 | 45 | 15 - 55 | 753 | 2 | 0 | 714.2 | 676 | 351 | 311 | 78 | 278 | 20 | 637 | 1.33 | 3.92 | |
Postseason
| Pitching Statistics | |||||||||||||||||
| Year | Team | Round | W | L | Sv-Op | G | GS | CG | IP | H | R | ER | HR | BB | IBB | K | ERA |
| 2011 | Ari | Total | 0 | 0 | 0 - 0 | 4 | 0 | 0 | 4.0 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 0.00 |
| LDS | 0 | 0 | 0 - 0 | 4 | 0 | 0 | 4.0 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 0.00 | ||
| 2013 | Cle | Total | 0 | 0 | 0 - 0 | 1 | 0 | 0 | 1.2 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0.00 |
| WC | 0 | 0 | 0 - 0 | 1 | 0 | 0 | 1.2 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0.00 | ||
| 2016 | Cle | Total | 2 | 1 | 0 - 0 | 11 | 0 | 0 | 10.1 | 14 | 7 | 5 | 1 | 5 | 3 | 12 | 4.35 |
| LDS | 0 | 0 | 0 - 0 | 3 | 0 | 0 | 2.1 | 2 | 2 | 2 | 1 | 0 | 0 | 1 | 7.71 | ||
| LCS | 2 | 0 | 0 - 0 | 4 | 0 | 0 | 3.1 | 6 | 2 | 1 | 0 | 1 | 1 | 4 | 2.70 | ||
| WS | 0 | 1 | 0 - 0 | 4 | 0 | 0 | 4.2 | 6 | 3 | 2 | 0 | 4 | 2 | 7 | 3.86 | ||
| 2017 | Cle | Total | 0 | 0 | 0 - 0 | 3 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 0 | 0 | 5 | 1.50 |
| LDS | 0 | 0 | 0 - 0 | 3 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 0 | 0 | 5 | 1.50 | ||
| Career | 2 | 1 | 0 - 0 | 19 | 0 | 0 | 22.0 | 19 | 8 | 6 | 2 | 6 | 3 | 22 | 2.45 | ||
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