Transactions
| Date | Player | Pos | Transactions |
| 5/26 | Romeo Doubs | WR | signed/draft choice Four-year contract (through 2025) |
| 5/26 | Zach Tom | C | signed/draft choice Four-year contract (through 2025) |
| 5/24 | Chris Slayton | DT | acquired from waiver |
| 5/20 | JJ Molson | K | cut |
| 5/18 | Jack Coco | TE | signed |
| 5/17 | Jahmir Johnson | T | cut |
| 5/16 | Jaire Alexander | CB | re-signed Four-year extension (through 2026) |
| 5/11 | Eli Wolf | TE | acquired from waiver |
| 5/11 | Chris Blair | WR | cut |
| 5/9 | Rasheed Walker | T | signed/draft choice Four-year contract (through 2025) |
| 5/9 | Kobe Jones | LB | signed |
| 5/6 | Quay Walker | LB | signed/draft choice Four-year contract (fifth-year option) |
| 5/6 | Devonte Wyatt | DT | signed/draft choice Four-year contract (fifth-year option) |
| 5/6 | Sean Rhyan | T | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Kingsley Enagbare | LB | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Tariq Carpenter | S | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Jonathan Ford | DT | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Samori Toure | WR | signed/draft choice Four-year contract (through 2025) |
| 5/2 | Caliph Brice | LB | signed |
| 5/2 | B.J. Baylor | RB | signed |
| 5/2 | Ellis Brooks | LB | signed |
| 5/2 | Akial Byers | DT | signed |
| 5/2 | Danny Davis III | WR | signed |
| 5/2 | Tyler Goodson | RB | signed |
| 5/2 | Jahmir Johnson | T | signed |
| 5/2 | Caleb Jones | T | signed |
| 5/2 | Chauncey Manac | LB | signed |
| 5/2 | George Moore | G | signed |
| 5/2 | Hauati Pututau | DT | signed |
| 5/2 | Cole Schneider | C | signed |
| 5/2 | Tre Sterling | S | signed |
| 5/2 | Raleigh Texada | CB | signed |
| 4/29 | Darnell Savage | S | team exercises option Fifth-year option on rookie contract |
| 4/29 | Rashan Gary | LB | team exercises option Fifth-year option on rookie contract |
| 4/18 | Krys Barnes | LB | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Dominique Dafney | TE | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Jake Hanson | C | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Yosh Nijman | T | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Randy Ramsey | LB | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Malik Taylor | WR | re-signed/excl. FA One-year contract (through 2022) |
| 4/14 | Sammy Watkins | WR | signed/unrest FA One-year contract (through 2022) |
| 4/6 | Whitney Mercilus | LB | retired |
| 3/26 | Keisean Nixon | CB | signed/unrest FA One-year contract (through 2022) |
| 3/22 | Jarran Reed | DT | signed/unrest FA One-year contract (through 2022) |
| 3/21 | Robert Tonyan | TE | re-signed/unrest FA One-year contract (through 2022) |
| 3/20 | Rasul Douglas | CB | re-signed/unrest FA Three-year contract (through 2024) |
| 3/17 | Pat O'Donnell | P | signed/unrest FA Two-year contract (through 2023) |
| 3/16 | Lucas Patrick | G | Declared Free Agent |
| 3/16 | Corey Bojorquez | P | Declared Free Agent |
| 3/16 | Oren Burks | LB | Declared Free Agent |
| 3/16 | Rasul Douglas | CB | Declared Free Agent |
| 3/16 | Dennis Kelly | T | Declared Free Agent |
| 3/16 | Kevin King | CB | Declared Free Agent |
| 3/16 | Tyler Lancaster | DT | Declared Free Agent |
| 3/16 | Whitney Mercilus | LB | Declared Free Agent |
| 3/16 | Equanimeous St. Brown | WR | Declared Free Agent |
| 3/16 | Chandon Sullivan | CB | Declared Free Agent |
| 3/16 | Robert Tonyan | TE | Declared Free Agent |
| 3/16 | Marquez Valdes-Scantling | WR | Declared Free Agent |
| 3/16 | Allen Lazard | WR | Restricted Free Agent |
| 3/16 | Henry Black | S | Declared Free Agent |
| 3/16 | Chauncey Rivers | LB | Declared Free Agent |
| 3/14 | Preston Smith | LB | re-signed Four-year extention (through 2026) |
| 3/14 | Za'Darius Smith | LB | cut |
| 3/14 | Billy Turner | G | cut |
| 3/14 | De'Vondre Campbell | LB | re-signed Five-year contract (through 2026) |
| 3/8 | Aaron Rodgers | QB | re-signed Four-year contract (through 2025) |
| 3/8 | Davante Adams | WR | Designated franchise player non-exclusive franchise tag |
| 2/22 | Dominik Eberle | K | signed |
Last updated May 28, 1:18 A.M. ET
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