Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Chris Hubbard | Jedrick Wills Jr. | Alex Taylor |
| Left Guard | Michael Dunn | Blake Hance | Cordel Iwuagwu |
| Center | JC Tretter | Nick Harris | Javon Patterson |
| Right Guard | Wyatt Teller | Joel Bitonio | Colby Gossett |
| Right Tackle | Jack Conklin | Blake Hance | Greg Senat |
| Wide Receiver | Odell Beckham Jr. | Donovan Peoples-Jones | KhaDarel Hodge |
| Wide Receiver | Jarvis Landry | Rashard Higgins | Alexander Hollins |
| Running Back | Nick Chubb | Kareem Hunt | John Kelly |
| Tight End | Austin Hooper | Harrison Bryant | David Njoku |
| Quarterback | Baker Mayfield | Case Keenum | Kyle Lauletta |
| Defense | |||
| Position | |||
| Left Defensive End | Myles Garrett | Porter Gustin | Cameron Malveaux |
| Left Defensive Tackle | Sheldon Richardson | Jordan Elliott | |
| Right Defensive Tackle | Andrew Billings | Malik Jackson | |
| Right Defensive End | Takkarist McKinley | Joe Jackson | |
| Strong Linebacker | Sione Takitaki | Malcolm Smith | |
| Middle Linebacker | Anthony Walker | Elijah Lee | |
| Weak Linebacker | Mack Wilson | Jacob Phillips | Montrel Meander |
| Left Cornerback | Denzel Ward | Troy Hill | M.J. Stewart |
| Right Cornerback | Greedy Williams | Robert Jackson | A.J. Green |
| Strong Safety | Ronnie Harrison Jr. | John Johnson III | |
| Free Safety | Grant Delpit | Sheldrick Redwine | Jovante Moffatt |
| Special Teams | |||
| Position | |||
| Kicker | Cody Parkey | Matt McCrane | |
| Kick-Offs | Cody Parkey | Matt McCrane | |
| Punter | Jamie Gillan | ||
| Kick Returner | Donovan Peoples-Jones | JoJo Natson | |
| Punt Returner | D'Ernest Johnson | Donovan Peoples-Jones | |
| Holder | Jamie Gillan | ||
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