Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Terron Armstead | James Hurst | Ethan Greenidge |
| Left Guard | Andrus Peat | ||
| Center | Erik McCoy | Will Clapp | |
| Right Guard | Cesar Ruiz | Derrick Kelly II | |
| Right Tackle | Ryan Ramczyk | ||
| Wide Receiver | Emmanuel Sanders | Juwan Johnson | |
| Running Back | Alvin Kamara | Latavius Murray | Dwayne Washington |
| Tight End | Jared Cook | Josh Hill | Adam Trautman |
| Quarterback | Drew Brees | Taysom Hill | Jameis Winston |
| Defense | |||
| Position | |||
| Left Defensive End | Cameron Jordan | Carl Granderson | |
| Left Defensive Tackle | David Onyemata | Malcom Brown | |
| Right Defensive Tackle | Sheldon Rankins | Shy Tuttle | |
| Right Defensive End | Trey Hendrickson | Marcus Davenport | Malcolm Roach |
| Strong Linebacker | Zack Baun | ||
| Middle Linebacker | Alex Anzalone | Craig Robertson | |
| Weak Linebacker | Demario Davis | Kaden Elliss | |
| Left Cornerback | Janoris Jenkins | P.J. Williams | Justin Hardee Sr. |
| Right Cornerback | Marshon Lattimore | Ken Crawley | |
| Strong Safety | Malcolm Jenkins | Chauncey Gardner-Johnson | J.T. Gray |
| Free Safety | Marcus Williams | D.J. Swearinger | |
| Special Teams | |||
| Position | |||
| Kicker | Wil Lutz | ||
| Kick-Offs | Wil Lutz | ||
| Punter | Thomas Morstead | ||
| Kick Returner | Ty Montgomery | Taysom Hill | |
| Punt Returner | Marquez Callaway | ||
| Holder | Thomas Morstead | Taysom Hill | |
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