NFL Football

Final 1 2 3 4 Tot
San Francisco 0 7 0 10 17
Philadelphia 3 0 0 8 11
10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET17:00 GMT1:00 10:00 AM MST12:00 PM EST11:00 AM CT21:00 UAE13:00 ET16:00 , September 19, 2021
Lincoln Financial Field, Philadelphia, Pennsylvania  Weather: 75°, Clear  Attendance: 69,796

49ers-Eagles Preview

According to STATS
According to STATS

San Francisco 49ers at Philadelphia Eagles

  1. San Francisco and Philadelphia are meeting for the second consecutive season with the Eagles notching a 25-20 road win at the 49ers last October. Four of the last five games between the teams have been decided by five points or fewer.
  2. In Sunday's 41-33 win over Detroit, the 49ers scored 31 points in the first half, which was the most points in a first half for the Niners since scoring 35 points against the Rams in 2008. It was also the fifth time that San Francisco has scored 40 or more points in a season opener.
  3. Philadelphia kicked off its season with a 32-6 victory over Atlanta with a touchdown in all four quarters. In 2020, the Eagles were one of two NFL teams to not score 30 points in any game (along with the New York Jets).
  4. Rookie RB Eli Mitchell rushed for 104 yards and a TD in his debut for San Francisco. A sixth-round pick, Mitchell is the first player drafted in the sixth round or later to have 100 rushing yards in a week one debut since the undrafted Ronnie Coleman rushed for 123 yards for the Houston Oilers in 1975.
  5. Jalen Hurts completed 27 of 35 passes (77.1 percent), threw three TDs and no INTs in Philadelphia's season opener against Atlanta. Hurts is the fourth Eagles QB since the merger to have a game with three or more passing TDs, no INTs, and a completion percentage above 75 percent, joining Donovan McNabb (3x), Randall Cunningham (2x), and Nick Foles.
  6. Trey Lance, the third pick in the 2021 NFL Draft, threw a five-yard touchdown to Trent Sherfield on the first pass of his professional career in San Francisco's 41-33 win over Detroit. At 21 years and 126 days old, Lance became the youngest player in the Super Bowl era to throw a touchdown on his first NFL pass.
Team Comparison

San Francisco
41.0 Points 32.0
319.0 Pass Yds 264.0
131.0 Rush Yds 173.0
1 Takeaways 0
(AP Photo/Duane Burleson)

Jalen Hurts won over the city of Philadelphia with one outstanding performance.

Now he gets to play in front of a packed stadium at home for the first time knowing how well he played last week won't matter. As he says often, "Rent is due every day."

"A game with electric fans, passionate fans, I'm looking forward to it," Hurts said. "Anywhere you go, you want to play at a high level."

Hurts completed 77.1% of his passes for 264 yards and three touchdowns last week in a 32-6 win at Atlanta. He leads the Eagles (1-0) against the San Francisco 49ers (1-0) on Sunday, looking to help the team start 2-0 for the first time since 2017, when it went on to win the Super Bowl.

Eagles coach Nick Sirianni was impressive in his NFL coaching debut. The 49ers present a tougher challenge. They'll know more about Sirianni's scheme than the Falcons did because the Eagles didn't show much in the preseason.

"Practices were crisp last week, and we stepped on the field and were ready to play that game," Sirianni said. "If we don't have good practices this week, we're not going to be ready. It's being in that mindset, that dog mentality to put yourself in position to go out and win the game on Sunday."

The Niners are coming off a 41-33 win at Detroit in which they had a 28-point lead in the third quarter. They were missing quarterback Jimmy Garoppolo in a 25-20 home loss to Philadelphia last October. George Kittle had a career-best 15 catches for 183 yards in that game.


The 49ers have rotated backs throughout coach Kyle Shanahan's tenure with a different player leading the team in rushing each year. With Raheem Mostert out with a season-ending knee injury, that streak will increase to five straight years. Sixth-round rookie Elijah Mitchell stepped in for Mostert last week and became the first rookie not drafted in the first three rounds since Ronnie Coleman in 1974 to rush for at least 100 yards in a season opener with 104 yards on 19 carries. Third-rounder Trey Sermon should be active this week and Jamycal Hasty is also an option.

"They're a good group," Garoppolo said. "They really are. They complement each other really well. It's a little bit of different tastes with each one of them. They each have their own style of doing it, but it's all effective. And I think with the O-line we've got, tight ends, fullbacks, even receivers blocking it. It makes for a good group."


The Eagles dominated the line of scrimmage against the Falcons as their offensive line was exceptional despite seven penalties. Left tackle Jordan Mailata had a crunching, highlight-reel block on a TD pass. Center Jason Kelce shoved aside two defenders on the same run play several yards downfield. Nick Bosa, Fred Warner and the rest of San Francisco's defense won't be so easy to push around. On the defensive side, tackle Javon Hargrave had two sacks and the entire unit put pressure on Matt Ryan.


The Niners once again opted to stay on the East Coast between games to cut down on the cross-country travel. They practiced all week at The Greenbrier resort in West Virginia, where they spent a week last September between games. San Francisco also stayed on the road twice in 2019 and has won the second game on all three of those trips, averaging 41.7 points in those games. The Niners are glad to be back at a facility they've spent time at before.

"Any time you know what you're getting into, I think it always helps," Shanahan said. "The unknown to me when you get off your routine is what messes guys up a little bit, but that's why we like coming here. They do it awesome, but we also know exactly what we're getting into."


Brandon Aiyuk wasn't targeted once in 27 snaps in the opener despite coming off a promising rookie year when he led the Niners with 60 catches for 748 yards. Aiyuk was slowed by a hamstring injury in training camp and fell behind Trent Sherfield, who had two catches for 23 yards in the opener.

"Aiyuk's been a little inconsistent because he's been in and out with his injury," Shanahan said. "That's what we felt was the best chance for us last week. Aiyuk's still got a chance to get that spot up and not rotate as much."


Eagles rookie receiver DeVonta Smith caught a TD pass and had a team-high 71 yards receiving on six catches in the opener. Fellow rookie back Kenneth Gainwell also scored a TD and added 43 yards from scrimmage.


AP Pro Football Writer Josh Dubow contributed to this report.


More AP NFL coverage: and

Updated September 16, 2021

Sports Data API Powered by STATS © 2021 by STATS PERFORM.
Any commercial use or distribution without the express written consent of STATS PERFROM is strictly prohibited.