NFL Leaders |
Rushing First Downs
| Rank | Name | Team | Stats |
| 1 | J. Jacobs | LV | 93 |
| 2 | N. Chubb | Cle | 69 |
| 3 | J. Hurts | Phi | 67 |
| 4t | J. Fields | Chi | 65 |
| 4t | D. Henry | Ten | 65 |
| 4t | J. Williams | Det | 65 |
| 7t | S. Barkley | NYG | 62 |
| 7t | M. Sanders | Phi | 62 |
| 9 | C. McCaffrey | SF | 59 |
| 10 | D. Jones | NYG | 57 |
| 11 | J. Allen | Buf | 55 |
| 12t | A. Jones | GB | 54 |
| 12t | D. Pierce | Hou | 54 |
| 14 | T. Allgeier | Atl | 53 |
| 15t | E. Elliott | Dal | 52 |
| 15t | T. Etienne Jr. | Jax | 52 |
| 17 | K. Walker III | Sea | 51 |
| 18t | D. Cook | Min | 50 |
| 18t | B. Robinson Jr. | Was | 50 |
| 20 | R. Stevenson | NE | 49 |
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