NFL Leaders |
Passes Defensed
| Rank | Name | Team | G | TK | Sacks | Sack-Yds | Int | Fum | PD |
| 1 | S. Gardner | NYJ | 17 | 75 | 0.0 | 0.0 | 2 | 0 | 20 |
| 2 | J. Ramsey | LAR | 17 | 88 | 2.0 | 17.0 | 4 | 3 | 18 |
| 3 | J. Bradberry | Phi | 17 | 44 | 0.0 | 0.0 | 3 | 0 | 17 |
| 4t | D. Williams | Jax | 17 | 53 | 0.0 | 0.0 | 0 | 0 | 16 |
| 4t | T. Woolen | Sea | 17 | 63 | 0.0 | 0.0 | 6 | 0 | 16 |
| 6t | T. Campbell | Jax | 17 | 70 | 0.0 | 0.0 | 3 | 1 | 15 |
| 6t | M. Davis | LAC | 17 | 61 | 1.0 | 6.0 | 1 | 0 | 15 |
| 6t | M. Emerson Jr. | Cle | 17 | 63 | 1.0 | 7.0 | 0 | 0 | 15 |
| 6t | P. Peterson | Min | 17 | 66 | 0.0 | 0.0 | 5 | 0 | 15 |
| 6t | C. Sutton | Pit | 16 | 43 | 0.0 | 0.0 | 3 | 0 | 15 |
| 6t | D. Ward | Cle | 14 | 53 | 0.0 | 0.0 | 3 | 0 | 15 |
| 12t | J. Alexander | GB | 16 | 56 | 0.0 | 0.0 | 5 | 0 | 14 |
| 12t | T. Diggs | Dal | 17 | 59 | 0.0 | 0.0 | 3 | 0 | 14 |
| 12t | D. Slay | Phi | 17 | 55 | 0.0 | 0.0 | 3 | 0 | 14 |
| 15t | R. Douglas | GB | 17 | 76 | 1.0 | 0.0 | 4 | 1 | 13 |
| 15t | K. Fuller | Was | 17 | 52 | 0.0 | 0.0 | 3 | 0 | 13 |
| 15t | L. Wallace | Pit | 15 | 48 | 0.0 | 0.0 | 4 | 0 | 13 |
| 18t | C. Davis III | TB | 13 | 63 | 0.0 | 0.0 | 1 | 1 | 12 |
| 18t | X. Howard | Mia | 15 | 45 | 0.0 | 0.0 | 1 | 0 | 12 |
| 18t | D. Jackson | Buf | 15 | 57 | 0.0 | 0.0 | 2 | 1 | 12 |
| 18t | M. Jackson | Sea | 17 | 74 | 0.0 | 0.0 | 1 | 0 | 12 |
| 18t | R. Jenkins | Jax | 17 | 112 | 1.0 | 0.0 | 3 | 3 | 12 |
| 18t | D. Reed Jr. | NYJ | 17 | 80 | 0.0 | 0.0 | 1 | 1 | 12 |
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