NFL Leaders |
Rushing First Downs
| Rank | Name | Team | Stats |
| 1 | J. Taylor | Ind | 107 |
| 2 | A. Gibson | Was | 65 |
| 3 | N. Harris | Pit | 62 |
| 4 | N. Chubb | Cle | 61 |
| 5 | J. Mixon | Cin | 60 |
| 6 | D. Cook | Min | 57 |
| 7 | J. Hurts | Phi | 56 |
| 8t | E. Elliott | Dal | 55 |
| 8t | D. Harris | NE | 55 |
| 8t | D. Montgomery | Chi | 55 |
| 11 | J. Allen | Buf | 54 |
| 12t | J. Conner | Ari | 53 |
| 12t | A. Ekeler | LAC | 53 |
| 14 | J. Williams | Den | 52 |
| 15 | A. Dillon | GB | 50 |
| 16t | D. Henry | Ten | 49 |
| 16t | S. Michel | LAR | 49 |
| 18t | M. Gordon III | Den | 48 |
| 18t | L. Jackson | Bal | 48 |
| 20 | E. Mitchell | SF | 47 |
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