| Friday, 1 January 2021 |
| Time/Result | Home | Away | Venue |
| 0-1 |
Everton |
West Ham United | Goodison Park |
| 2-1 |
Manchester United |
Aston Villa | Old Trafford |
| Saturday, 2 January 2021 |
| Time/Result | Home | Away | Venue |
| 3-0 |
Tottenham Hotspur |
Leeds United | Tottenham Hotspur Stadium |
| 2-0 |
Crystal Palace |
Sheffield United | Selhurst Park |
| 3-3 |
Brighton & Hove Albion |
Wolves | The American Express Community Stadium |
| 0-4 |
West Bromwich Albion |
Arsenal | The Hawthorns |
| Sunday, 3 January 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
Burnley |
Fulham | Turf Moor |
| 1-2 |
Newcastle United |
Leicester City | St. James' Park |
| 1-3 |
Chelsea |
Manchester City | Stamford Bridge |
| Monday, 4 January 2021 |
| Time/Result | Home | Away | Venue |
| 1-0 |
Southampton |
Liverpool | St. Mary's Stadium |
| Tuesday, 12 January 2021 |
| Time/Result | Home | Away | Venue |
| 1-0 |
Sheffield United |
Newcastle United | Bramall Lane |
| 1-2 |
Wolves |
Everton | Molineux Stadium |
| 0-1 |
Burnley |
Manchester United | Turf Moor |
| Wednesday, 13 January 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
Aston Villa |
Tottenham Hotspur | Villa Park |
| 1-0 |
Manchester City |
Brighton & Hove Albion | Etihad Stadium |
| 1-1 |
Tottenham Hotspur |
Fulham | Tottenham Hotspur Stadium |
| Thursday, 14 January 2021 |
| Time/Result | Home | Away | Venue |
| 0-0 |
Arsenal |
Crystal Palace | Emirates Stadium |
| Saturday, 16 January 2021 |
| Time/Result | Home | Away | Venue |
| 2-3 |
Wolves |
West Bromwich Albion | Molineux Stadium |
| 0-1 |
Leeds United |
Brighton & Hove Albion | Elland Road |
| 1-0 |
West Ham United |
Burnley | London Stadium |
| 0-1 |
Fulham |
Chelsea | Craven Cottage |
| 2-0 |
Leicester City |
Southampton | King Power Stadium |
| Sunday, 17 January 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
Aston Villa |
Everton | Villa Park |
| 1-3 |
Sheffield United |
Tottenham Hotspur | Bramall Lane |
| 0-0 |
Liverpool |
Manchester United | Anfield |
| 4-0 |
Manchester City |
Crystal Palace | Etihad Stadium |
| Monday, 18 January 2021 |
| Time/Result | Home | Away | Venue |
| 3-0 |
Arsenal |
Newcastle United | Emirates Stadium |
| Tuesday, 19 January 2021 |
| Time/Result | Home | Away | Venue |
| 2-1 |
West Ham United |
West Bromwich Albion | London Stadium |
| 2-0 |
Leicester City |
Chelsea | King Power Stadium |
| Wednesday, 20 January 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
Leeds United |
Southampton | Elland Road |
| 2-0 |
Manchester City |
Aston Villa | Etihad Stadium |
| 1-2 |
Fulham |
Manchester United | Craven Cottage |
| Thursday, 21 January 2021 |
| Time/Result | Home | Away | Venue |
| 0-1 |
Liverpool |
Burnley | Anfield |
| Saturday, 23 January 2021 |
| Time/Result | Home | Away | Venue |
| 2-0 |
Aston Villa |
Newcastle United | Villa Park |
| Tuesday, 26 January 2021 |
| Time/Result | Home | Away | Venue |
| 1-2 |
Newcastle United |
Leeds United | St. James' Park |
| 2-3 |
Crystal Palace |
West Ham United | Selhurst Park |
| 1-3 |
Southampton |
Arsenal | St. Mary's Stadium |
| 0-5 |
West Bromwich Albion |
Manchester City | The Hawthorns |
| Wednesday, 27 January 2021 |
| Time/Result | Home | Away | Venue |
| 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST13:00 ET13:00 14:00 BRT14:00 11:00 AM CT |
Chelsea |
Wolves | Stamford Bridge |
| 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST13:00 ET13:00 14:00 BRT14:00 11:00 AM CT |
Burnley |
Aston Villa | Turf Moor |
| 11:30 AM PT12:30 PM MT1:30 PM CT2:30 PM ET19:30 GMT20:30 19:30 7:30 PM 21:30 KSA6:30 AM AET1:00 (+1) IST3:00 PM VEN23:30 UAE3:30 AM SST3:30 2:30 12:30 PM MST1:30 PM CST2:30 PM EST14:30 ET14:30 15:30 BRT15:30 12:30 PM CT |
Brighton & Hove Albion |
Fulham | The American Express Community Stadium |
| 12:15 PM PT1:15 PM MT2:15 PM CT3:15 PM ET20:15 GMT21:15 20:15 8:15 PM 22:15 KSA7:15 AM AET1:45 (+1) IST3:45 PM VEN0:15 (+1) UAE4:15 AM SST4:15 3:15 1:15 PM MST2:15 PM CST3:15 PM EST15:15 ET15:15 16:15 BRT16:15 1:15 PM CT |
Everton |
Leicester City | Goodison Park |
| 12:15 PM PT1:15 PM MT2:15 PM CT3:15 PM ET20:15 GMT21:15 20:15 8:15 PM 22:15 KSA7:15 AM AET1:45 (+1) IST3:45 PM VEN0:15 (+1) UAE4:15 AM SST4:15 3:15 1:15 PM MST2:15 PM CST3:15 PM EST15:15 ET15:15 16:15 BRT16:15 1:15 PM CT |
Manchester United |
Sheffield United | Old Trafford |
| Thursday, 28 January 2021 |
| Time/Result | Home | Away | Venue |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
Tottenham Hotspur |
Liverpool | Tottenham Hotspur Stadium |
| Saturday, 30 January 2021 |
| Time/Result | Home | Away | Venue |
| 4:30 AM PT5:30 AM MT6:30 AM CT7:30 AM ET12:30 GMT13:30 12:30 12:30 PM 14:30 KSA11:30 PM AET18:00 IST8:00 AM VEN16:30 UAE8:30 PM SST20:30 19:30 5:30 AM MST6:30 AM CST7:30 AM EST7:30 ET7:30 8:30 BRT8:30 5:30 AM CT |
Everton |
Newcastle United | Goodison Park |
| 7:00 AM PT8:00 AM MT9:00 AM CT10:00 AM ET15:00 GMT16:00 15:00 3:00 PM 17:00 KSA2:00 AM AET20:30 IST10:30 AM VEN19:00 UAE11:00 PM SST23:00 22:00 8:00 AM MST9:00 AM CST10:00 AM EST10:00 ET10:00 11:00 BRT11:00 8:00 AM CT |
Manchester City |
Sheffield United | Etihad Stadium |
| 7:00 AM PT8:00 AM MT9:00 AM CT10:00 AM ET15:00 GMT16:00 15:00 3:00 PM 17:00 KSA2:00 AM AET20:30 IST10:30 AM VEN19:00 UAE11:00 PM SST23:00 22:00 8:00 AM MST9:00 AM CST10:00 AM EST10:00 ET10:00 11:00 BRT11:00 8:00 AM CT |
Crystal Palace |
Wolves | Selhurst Park |
| 7:00 AM PT8:00 AM MT9:00 AM CT10:00 AM ET15:00 GMT16:00 15:00 3:00 PM 17:00 KSA2:00 AM AET20:30 IST10:30 AM VEN19:00 UAE11:00 PM SST23:00 22:00 8:00 AM MST9:00 AM CST10:00 AM EST10:00 ET10:00 11:00 BRT11:00 8:00 AM CT |
West Bromwich Albion |
Fulham | The Hawthorns |
| 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET17:30 GMT18:30 17:30 5:30 PM 19:30 KSA4:30 AM AET23:00 IST1:00 PM VEN21:30 UAE1:30 AM SST1:30 0:30 10:30 AM MST11:30 AM CST12:30 PM EST12:30 ET12:30 13:30 BRT13:30 10:30 AM CT |
Arsenal |
Manchester United | Emirates Stadium |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
Southampton |
Aston Villa | St. Mary's Stadium |
| Sunday, 31 January 2021 |
| Time/Result | Home | Away | Venue |
| 4:00 AM PT5:00 AM MT6:00 AM CT7:00 AM ET12:00 GMT13:00 12:00 12:00 PM 14:00 KSA11:00 PM AET17:30 IST7:30 AM VEN16:00 UAE8:00 PM SST20:00 19:00 5:00 AM MST6:00 AM CST7:00 AM EST7:00 ET7:00 8:00 BRT8:00 5:00 AM CT |
Chelsea |
Burnley | Stamford Bridge |
| 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET14:00 GMT15:00 14:00 2:00 PM 16:00 KSA1:00 AM AET19:30 IST9:30 AM VEN18:00 UAE10:00 PM SST22:00 21:00 7:00 AM MST8:00 AM CST9:00 AM EST9:00 ET9:00 10:00 BRT10:00 7:00 AM CT |
Leicester City |
Leeds United | King Power Stadium |
| 8:30 AM PT9:30 AM MT10:30 AM CT11:30 AM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST11:30 ET11:30 12:30 BRT12:30 9:30 AM CT |
West Ham United |
Liverpool | London Stadium |
| 11:15 AM PT12:15 PM MT1:15 PM CT2:15 PM ET19:15 GMT20:15 19:15 7:15 PM 21:15 KSA6:15 AM AET0:45 (+1) IST2:45 PM VEN23:15 UAE3:15 AM SST3:15 2:15 12:15 PM MST1:15 PM CST2:15 PM EST14:15 ET14:15 15:15 BRT15:15 12:15 PM CT |
Brighton & Hove Albion |
Tottenham Hotspur | The American Express Community Stadium |
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