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| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 23 - Sep. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Anastasia Pavlyuchenkova | Loss | 2-6, 3-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Win | 6-2, 2-6, 6-3 |
| Second Round | Claire Liu | Win | 6-3, 6-1 |
| Third Round | Ekaterina Makarova | Win | 4-6, 6-1, 6-2 |
| Fourth Round | Elina Svitolina | Win | 6-3, 1-6, 6-0 |
| Quarterfinals | Sloane Stephens | Win | 6-2, 6-3 |
| Semifinals | Serena Williams | Loss | 3-6, 0-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Camila Giorgi | Loss | 2-6, 3-6 |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 6 - Aug. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Aleksandra Krunic | Win | 6-1, 6-0 |
| Second Round | Monica Puig | Win | 4-6, 7-6 (11-9), 6-1 |
| Third Round | Julia Goerges | Win | 6-3, 7-6 (7-2) |
| Quarterfinals | Sloane Stephens | Loss | 2-6, 2-6 |
| Moscow River Cup presented by O1 Properties | ||
| Surface: Hard | Date: Jul. 23 - Jul. 29 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Pauline Parmentier | Win | 6-2, 3-6, 6-4 |
| Second Round | Irina Bara | Win | 6-2, 6-7 (5-7), 6-4 |
| Quarterfinals | Aliaksandra Sasnovich | Loss | Retired |
| BRD Bucharest Open | ||
| Surface: Red Clay | Date: Jul. 16 - Jul. 22 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Dalila Jakupovic | Win | 4-6, 6-2, 7-6 (7-1) |
| Second Round | Arantxa Rus | Win | 6-1, 7-5 |
| Quarterfinals | Sorana Cirstea | Win | 3-6, 6-3, 6-2 |
| Semifinals | Polona Hercog | Win | 6-1, 0-0 Retired |
| Final | Petra Martic | Win | 7-6 (7-4), 6-2 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Camila Giorgi | Loss | 1-6, 6-2, 4-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 24 - Jun. 30 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Harriet Dart | Win | 6-3, 6-4 |
| Third Round | Daria Kasatkina | Loss | 4-6, 4-6 |
| Mallorca Open | ||
| Surface: Grass | Date: Jun. 18 - Jun. 24 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Svetlana Kuznetsova | Win | 6-3, 6-3 |
| Second Round | Antonia Lottner | Win | 1-6, 6-3, 6-1 |
| Quarterfinals | Ajla Tomljanovic | Win | 3-6, 6-3, 6-1 |
| Semifinals | Samantha Stosur | Win | 7-6 (7-1), 6-1 |
| Final | Tatjana Maria | Loss | 4-6, 5-7 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Mariana Duque-Marino | Loss | 6-4, 1-6, 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Win | 6-3, 3-0 Retired |
| Second Round | Aleksandra Krunic | Win | 6-4, 6-4 |
| Third Round | Caroline Wozniacki | Loss | 2-6, 7-5, 3-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Anna Karolina Schmiedlova | Win | 6-3, 4-6, 6-3 |
| Second Round | Kiki Bertens | Loss | 1-6, 4-6 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 2 - Apr. 8 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Caroline Dolehide | Win | 7-5, 6-7 (5-7), 6-1 |
| Third Round | Ashleigh Barty | Win | 6-3, 6-4 |
| Quarterfinals | Kristyna Pliskova | Win | 6-4, 6-0 |
| Semifinals | Julia Goerges | Loss | 6-7 (5-7), 3-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alize Cornet | Win | 7-5, 6-4 |
| Third Round | Victoria Azarenka | Loss | 6-3, 4-6, 1-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Monica Puig | Win | 6-2, 2-6, 6-1 |
| Third Round | Julia Goerges | Win | 6-3, 6-3 |
| Fourth Round | Venus Williams | Loss | 6-7 (6-8), 4-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ekaterina Makarova | Loss | 6-3, 6-7 (9-11), 3-6 |
| Qatar Total Open | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Win | 6-3, 6-4 |
| Second Round | Naomi Osaka | Win | 6-4, 6-1 |
| Third Round | Simona Halep | Loss | 4-6, 3-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Varvara Lepchenko | Win | 3-6, 6-3, 6-2 |
| Second Round | Maria Sharapova | Loss | 1-6, 6-7 (4-7) |
| Sydney International | ||
| Surface: Hard | Date: Jan. 7 - Jan. 13 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Dominika Cibulkova | Loss | 3-6, 1-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 7 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Samantha Stosur | Win | 6-1, 6-3 |
| Second Round | Sorana Cirstea | Win | 6-2, 6-1 |
| Quarterfinals | Aleksandra Krunic | Win | 6-2, 6-4 |
| Semifinals | Aliaksandra Sasnovich | Loss | 6-7 (3-7), 4-6 |
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