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| European Open | ||
| Surface: Hard | Date: Oct. 14 - Oct. 20 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Gregoire Barrere | Win | 6-2, 6-1 |
| Second Round | Frances Tiafoe | Loss | 3-6, 4-6 |
| Rolex Shanghai Masters | ||
| Surface: Hard | Date: Oct. 6 - Oct. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Matteo Berrettini | Loss | 2-6, 1-6 |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Sep. 30 - Oct. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Go Soeda | Loss | 6-4, 6-7 (4-7), 3-6 |
| Moselle Open | ||
| Surface: Hard | Date: Sep. 16 - Sep. 22 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Pierre-Hugues Herbert | Loss | 6-7 (3-7), 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Casper Ruud | Win | 6-4, 6-4, 6-2 |
| Second Round | John Isner | Loss | 3-6, 6-7 (4-7), 6-7 (5-7) |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ivo Karlovic | Win | 7-5, 7-6 (7-4) |
| Second Round | Stefanos Tsitsipas | Win | 6-4, 6-7 (5-7), 7-6 (8-6) |
| Third Round | Daniil Medvedev | Loss | 2-6, 1-6 |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jo-Wilfried Tsonga | Win | 6-2, 6-2 |
| Second Round | Nikoloz Basilashvili | Loss | 6-2, 2-6, 3-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jordan Thompson | Loss | 7-6 (10-8), 4-6, 5-7 |
| Hamburg Open | ||
| Surface: Red Clay | Date: Jul. 22 - Jul. 28 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Thiago Monteiro | Win | 6-1, 6-3 |
| Second Round | Pablo Carreno Busta | Loss | 1-6, 6-7 (4-7) |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 33 |
| Round | Opponent | W / L | Result |
| First Round | Radu Albot | Win | 6-4, 6-3, 6-2 |
| Second Round | Taylor Fritz | Win | 6-4, 6-3, 5-7, 7-6(7-2) |
| Third Round | Mikhail Kukushkin | Loss | 3-6, 6-7 (5-7), 6-4, 5-7 |
| Noventi Open | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Laslo Djere | Win | 6-4, 6-4 |
| Second Round | Karen Khachanov | Loss | 3-6, 6-3, 4-6 |
| MercedesCup | ||
| Surface: Grass | Date: Jun. 10 - Jun. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Shapovalov | Win | 7-5, 6-4 |
| Second Round | Miomir Kecmanovic | Win | 6-2, 6-2 |
| Quarterfinals | Lucas Pouille | Win | 6-4, 6-4 |
| Semifinals | Matteo Berrettini | Loss | 4-6, 5-7 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Shapovalov | Win | 7-6 (7-1), 6-3, 6-4 |
| Second Round | Radu Albot | Win | 7-6 (7-2), 7-6 (7-3), 6-7 (4-7), 6-2 |
| Third Round | Borna Coric | Win | 4-6, 6-1, 4-6, 7-6(7-1), 11-9 |
| Fourth Round | Novak Djokovic | Loss | 3-6, 2-6, 2-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Grigor Dimitrov | Win | 6-4, 6-7 (5-7), 6-3 |
| Second Round | Marin Cilic | Win | 6-2, 6-3 |
| Third Round | Kei Nishikori | Loss | 6-3, 6-7 (2-7), 3-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nick Kyrgios | Win | 7-6 (7-4), 6-4 |
| Second Round | Marin Cilic | Loss | 6-4, 3-6, 4-6 |
| BMW Open by FWU | ||
| Surface: Red Clay | Date: Apr. 29 - May 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Thiago Monteiro | Loss | 1-6, 1-6 |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Hugo Dellien | Win | 6-3, 6-1 |
| Second Round | David Goffin | Win | 7-6 (8-6), 6-3 |
| Third Round | Stefanos Tsitsipas | Win | 6-4, 3-6, 6-2 |
| Quarterfinals | Rafael Nadal | Loss | 5-7, 5-7 |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Shapovalov | Win | 5-7, 6-3, 6-1 |
| Second Round | Grigor Dimitrov | Loss | 6-7 (2-7), 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Reilly Opelka | Loss | 6-4, 3-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | John Millman | Win | 6-1, 6-3 |
| Second Round | Ricardas Berankis | Win | 3-6, 6-3, 6-2 |
| Third Round | Alexander Zverev | Win | 6-3, 6-1 |
| Fourth Round | Milos Raonic | Loss | 4-6, 3-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 25 - Mar. 2 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Milos Raonic | Win | 6-4, 5-7, 6-4 |
| Second Round | Marton Fucsovics | Loss | 4-6, 2-6 |
| Garanti Koza Sofia Open | ||
| Surface: Hard | Date: Feb. 4 - Feb. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Stefano Travaglia | Win | 6-4, 6-3 |
| Second Round | Stefanos Tsitsipas | Loss | 6-7 (5-7), 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Matthew Ebden | Loss | 6-1, 4-6, 3-6, 4-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jeremy Chardy | Loss | 6-4, 3-6, 4-6 |
| ASB Classic | ||
| Surface: Hard | Date: Dec. 31 - Jan. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Laslo Djere | Win | 7-6 (7-5), 2-0 Retired |
| Second Round | Rubin Statham | Win | 6-2, 6-1 |
| Quarterfinals | Pablo Carreno Busta | Win | 7-6 (7-5), 6-7 (6-7), 7-6 (9-7) |
| Semifinals | Cameron Norrie | Loss | 5-7, 6-4, 3-6 |
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