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| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Steve Darcis | Win | 7-5, 6-3, 6-3 |
| Second Round | Denis Kudla | Loss | 5-7, 5-7, 6-0, 3-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | John Isner | Loss | 6-7 (3-7), 6-1, 5-7 |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nikoloz Basilashvili | Loss | 6-3, 4-6, 4-6 |
| Generali Open | ||
| Surface: Clay | Date: Jul. 29 - Aug. 3 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jeremy Chardy | Loss | 6-3, 4-6, 3-6 |
| J. Safra Sarasin Suisse Open Gstaad | ||
| Surface: Clay | Date: Jul. 22 - Jul. 28 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Denis Istomin | Win | 6-4, 6-7 (2-7), 7-6 (7-2) |
| Quarterfinals | Pablo Andujar | Loss | 6-7 (4-7), 4-6 |
| Plava Laguna Croatia Open Umag | ||
| Surface: Clay | Date: Jul. 15 - Jul. 21 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Andrey Rublev | Win | 6-4, 6-3 |
| Quarterfinals | Aljaz Bedene | Win | 5-7, 6-3, 6-3 |
| Semifinals | Salvatore Caruso | Win | 7-5, 0-0 Retired |
| Final | Attila Balazs | Win | 7-5, 7-5 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 32 |
| Round | Opponent | W / L | Result |
| First Round | Hubert Hurkacz | Loss | 3-6, 6-4, 4-6, 4-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 23 - Jun. 29 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sam Querrey | Loss | 2-6, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 30 |
| Round | Opponent | W / L | Result |
| First Round | Thiago Monteiro | Win | 6-3, 6-4, 6-4 |
| Second Round | Elliot Benchetrit | Win | 6-3, 6-3, 6-4 |
| Third Round | Alexander Zverev | Loss | 4-6, 2-6, 6-4, 6-1, 2-6 |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 19 - May 25 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Jo-Wilfried Tsonga | Loss | 6-7 (4-7), 4-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Laslo Djere | Loss | 4-6, 4-6 |
| Millennium Estoril Open | ||
| Surface: Red Clay | Date: Apr. 29 - May 5 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Leonardo Mayer | Loss | 6-7 (3-7), 4-6 |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Malek Jaziri | Win | 6-4, 6-4 |
| Second Round | David Goffin | Win | 6-3, 6-4 |
| Third Round | Dominic Thiem | Win | 6-3, 6-3 |
| Quarterfinals | Lorenzo Sonego | Win | 6-4, 7-5 |
| Semifinals | Daniil Medvedev | Win | 7-5, 6-1 |
| Final | Fabio Fognini | Loss | 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pablo Cuevas | Win | 6-4, 6-7 (6-8), 6-3 |
| Second Round | Kei Nishikori | Win | 2-6, 6-2, 6-3 |
| Third Round | Nick Kyrgios | Loss | 3-6, 1-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Taro Daniel | Win | 7-6 (8-6), 6-4 |
| Second Round | Marin Cilic | Loss | 3-6, 4-6 |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Feliciano Lopez | Loss | 7-6 (7-3), 2-6, 5-7 |
| Rio Open presented by Claro HDTV | ||
| Surface: Clay | Date: Feb. 18 - Feb. 24 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Cameron Norrie | Loss | 2-6, 1-6 |
| Argentina Open | ||
| Surface: Clay | Date: Feb. 11 - Feb. 17 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Leonardo Mayer | Loss | 3-6, 6-7 (3-7) |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pablo Cuevas | Loss | 4-6, 5-7, 1-6 |
| Sydney International | ||
| Surface: Hard | Date: Jan. 6 - Jan. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alex De Minaur | Loss | 4-6, 3-6 |
| Qatar ExxonMobil Open | ||
| Surface: Hard | Date: Dec. 31 - Jan. 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Adrian Mannarino | Win | 6-3, 7-6 (7-5) |
| Second Round | Ricardas Berankis | Win | 7-6 (7-4), 0-6, 7-5 |
| Quarterfinals | Marco Cecchinato | Loss | 6-7 (2-7), 2-6 |
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