Transactions
| Date | Player | Transactions |
| 4/12 | Chris Rusin, P | Signed to a Minor League Contract |
| 4/10 | Phillip Diehl, P | Designated for Assignment |
| 4/10 | Chris Owings, SS | Placed on 10-Day IL (Sprained left thumb) |
| 4/10 | Alan Trejo, SS | Purchased From Minors |
| 4/5 | Jairo Díaz, P | Outrighted to Minors |
| 4/1 | Kyle Freeland, P | Placed on 10-Day IL (Left shoulder strain) |
| 4/1 | Brendan Rodgers, SS | Placed on 10-Day IL (Strained right hamstring) |
| 3/31 | Jhoulys Chacín, P | Signed as Free Agent ( 2021)(one-year contract) |
| 3/31 | Jairo Díaz, P | Designated for Assignment |
| 3/27 | Lucas Gilbreath, P | Sent to Minors |
| 3/27 | Chi Chi González, P | Purchased From Minors |
| 3/27 | Scott Oberg, P | Placed on 60-Day IL (Recovery from blood clot procedure) |
| 3/27 | Colton Welker, 3B | Sent to Minors |
| 3/22 | Phillip Diehl, P | Sent to Minors |
| 3/22 | Antonio Santos, P | Sent to Minors |
| 3/20 | C.J. Cron, 1B | Purchased From Minors |
| 3/20 | Peter Lambert, P | Placed on 60-Day IL (Recovery from right elbow surgery) |
| 3/20 | Chris Owings, SS | Purchased From Minors |
| 3/16 | Yoan Aybar, P | Sent to Minors |
| 3/16 | Bret Boswell, 2B | Sent to Minors |
| 3/16 | Ryan Castellani, P | Sent to Minors |
| 3/16 | Justin Lawrence, P | Sent to Minors |
| 3/16 | José Mujica, P | Sent to Minors |
| 3/12 | Tommy Doyle, P | Sent to Minors |
| 3/12 | Elehuris Montero, 3B | Sent to Minors |
| 3/12 | Helcris Olivarez, P | Sent to Minors |
| 3/1 | Ian Desmond, CF | Placed on Restricted List (opting out of 2021 season) |
| 2/15 | C.J. Cron, 1B | Signed to a Minor League Contract |
| 2/11 | Greg Bird, 1B | Signed to a Minor League Contract |
| 2/1 | Austin Gomber, P | Traded St. Louis (for 3B Nolan Arenado, six-player trade) |
| 2/1 | Elehuris Montero, 3B | Traded St. Louis (for 3B Nolan Arenado, six-player trade) |
| 1/29 | Daniel Murphy, 2B | Retired |
| 1/29 | Chris Owings, SS | Signed to a Minor League Contract |
| 1/15 | Carlos Estévez, P | Signed ( 2021)(avoids arbitration) |
| 1/15 | Kyle Freeland, P | Signed ( 2021)(avoids arbitration) |
| 1/15 | Jon Gray, P | Signed ( 2021)(avoids arbitration) |
| 1/15 | Ryan McMahon, 2B | Signed ( 2021)(avoids arbitration) |
| 1/15 | Robert Stephenson, P | Signed ( 2021)(avoids arbitration) |
| 1/15 | Raimel Tapia, LF | Signed ( 2021)(avoids arbitration) |
| 1/14 | Mychal Givens, P | Signed ( 2021)(avoids arbitration) |
| 1/12 | Antonio Senzatela, P | Signed ( 2021)(avoids arbitration) |
| 1/11 | Wes Parsons, P | Signed to Play in Korea (DC Dinos) |
| 12/15 | Daniel Bard, P | Signed ( 2021)(avoids arbitration) |
| 12/12 | Chi Chi González, P | Signed to a Minor League Contract |
| 12/10 | Jordan Sheffield, P | Drafted Via Rule 5 |
| 12/3 | Yoan Aybar, P | Traded Boston (for INF Christian Koss) |
| 12/2 | David Dahl, LF | Free Agent - No Contract Offer (non-tendered) |
| 12/2 | Chi Chi González, P | Free Agent - No Contract Offer (non-tendered) |
| 12/2 | Tony Wolters, C | Free Agent - No Contract Offer (non-tendered) |
| 11/30 | Elias Díaz, C | Signed ( 2021)(avoids arbitration) |
| 11/25 | Jairo Díaz, P | Signed ( 2021)(avoids arbitration) |
| 11/25 | Robert Stephenson, P | Traded Cincinnati (for RHP Jeff Hoffman, four-player deal) |
| 11/25 | Jesus Tinoco, P | Outrighted to Minors |
| 11/21 | Connor Joe, LF | Signed to a Minor League Contract |
| 11/20 | Bret Boswell, 2B | Purchased From Minors |
| 11/20 | Lucas Gilbreath, P | Purchased From Minors |
| 11/20 | Ashton Goudeau, P | Designated for Assignment |
| 11/20 | Helcris Olivarez, P | Purchased From Minors |
| 11/20 | Jesus Tinoco, P | Designated for Assignment |
| 11/20 | Colton Welker, 3B | Purchased From Minors |
| 11/13 | José Briceño, C | Signed to a Minor League Contract |
| 11/9 | Dereck Rodríguez, P | Signed to a Minor League Contract |
| 11/1 | David Dahl, LF | Removed From 60-Day IL (Strained right shoulder) |
| 11/1 | Ian Desmond, CF | Reinstated From Restricted List |
| 11/1 | Peter Lambert, P | Removed From 60-Day IL (Right elbow surgery - out for season) |
| 11/1 | Scott Oberg, P | Removed From 60-Day IL (Blood clots in right arm) |
| 10/29 | Joe Harvey, P | Removed From 60-Day IL (Sprained right elbow) |
| 10/29 | Joe Harvey, P | Outrighted to Minors |
| 10/28 | Drew Butera, C | Declared Free Agency |
| 10/28 | Tim Collins, P | Reinstated From Restricted List |
| 10/28 | Matt Kemp, CF | Declared Free Agency |
| 10/28 | Daniel Murphy, 2B | Declared Free Agency |
| 10/28 | Chris Owings, SS | Declared Free Agency |
| 10/28 | Kevin Pillar, CF | Declared Free Agency |
| 10/28 | AJ Ramos, P | Declared Free Agency |
| 10/9 | James Pazos, P | Refused Minor League Assignment - Free Agent |
Last updated Apr. 13, 8:17 P.M. ET
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