Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Laremy Tunsil | Roderick Johnson | |
| Left Guard | Max Scharping | ||
| Center | Nick Martin | Greg Mancz | |
| Right Guard | Zach Fulton | ||
| Right Tackle | Tytus Howard | ||
| Wide Receiver | DeAndre Hopkins | ||
| Wide Receiver | Will Fuller V | Kenny Stills | |
| Wide Receiver | Keke Coutee | DeAndre Carter | |
| Running Back | Duke Johnson | Carlos Hyde | Taiwan Jones |
| Tight End | Darren Fells | Jordan Akins | |
| Quarterback | Deshaun Watson | AJ McCarron | |
| Defense | |||
| Position | |||
| Left Defensive End | Angelo Blackson | Charles Omenihu | |
| Nose Tackle | D.J. Reader | Brandon Dunn | |
| Right Defensive End | J.J. Watt | Carlos Watkins | |
| Left Outside Linebacker | Whitney Mercilus | Barkevious Mingo | |
| Left Inside Linebacker | Zach Cunningham | Dylan Cole | |
| Right Outside Linebacker | Brennan Scarlett | Jacob Martin | |
| Right Inside Linebacker | Benardrick McKinney | Peter Kalambayi | Tyrell Adams |
| Left Cornerback | Johnathan Joseph | Lonnie Johnson Jr. | |
| Right Cornerback | Bradley Roby | Gareon Conley | Keion Crossen |
| Strong Safety | Tashaun Gipson Sr. | Jahleel Addae | Mike Adams |
| Free Safety | Justin Reid | A.J. Moore Jr. | |
| Special Teams | |||
| Position | |||
| Kicker | Ka'imi Fairbairn | ||
| Kick-Offs | Ka'imi Fairbairn | ||
| Punter | Bryan Anger | ||
| Kick Returner | DeAndre Carter | Taiwan Jones | |
| Punt Returner | DeAndre Carter | Keke Coutee | |
| Holder | Bryan Anger | ||
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