Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Julie'n Davenport | Matt Kalil | Rick Leonard |
| Left Guard | Senio Kelemete | Max Scharping | David Steinmetz |
| Center | Nick Martin | Greg Mancz | |
| Right Guard | Zach Fulton | Maurquice Shakir | |
| Right Tackle | Seantrel Henderson | Tytus Howard | Martinas Rankin |
| Wide Receiver | DeAndre Hopkins | DeAndre Carter | Isaac Whitney |
| Wide Receiver | Will Fuller V | Jester Weah | Steven Mitchell Jr. |
| Wide Receiver | Vyncint Smith | Keke Coutee | |
| Running Back | Lamar Miller | D'Onta Foreman | Josh Ferguson |
| Tight End | Jordan Thomas | Jordan Akins | Kahale Warring |
| Quarterback | Deshaun Watson | AJ McCarron | Joe Webb III |
| Defense | |||
| Position | |||
| Left Defensive End | D.J. Reader | Charles Omenihu | Angelo Blackson |
| Nose Tackle | Brandon Dunn | ||
| Right Defensive End | J.J. Watt | Carlos Watkins | |
| Left Outside Linebacker | Whitney Mercilus | Brennan Scarlett | Chris Landrum |
| Left Inside Linebacker | Zach Cunningham | Dylan Cole | Peter Kalambayi |
| Right Outside Linebacker | Jadeveon Clowney | Davin Bellamy | |
| Right Inside Linebacker | Benardrick McKinney | Tyrell Adams | |
| Left Cornerback | Johnathan Joseph | Bradley Roby | Johnson Bademosi |
| Right Cornerback | Aaron Colvin | Lonnie Johnson Jr. | Jermaine Kelly Jr. |
| Strong Safety | Tashaun Gipson Sr. | Briean Boddy-Calhoun | A.J. Hendy |
| Free Safety | Justin Reid | Jahleel Addae | A.J. Moore |
| Special Teams | |||
| Position | |||
| Kicker | Ka'imi Fairbairn | ||
| Kick-Offs | Ka'imi Fairbairn | ||
| Punter | Trevor Daniel | ||
| Kick Returner | DeAndre Carter | Keke Coutee | |
| Punt Returner | DeAndre Carter | Keke Coutee | |
| Holder | Trevor Daniel | ||
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