Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Garett Bolles | Calvin Anderson | Quinn Bailey |
| Left Guard | Dalton Risner | Austin Schlottmann | |
| Center | Lloyd Cushenberry III | Graham Glasgow | Patrick Morris |
| Right Guard | Graham Glasgow | Netane Muti | |
| Right Tackle | Ja'Wuan James | ||
| Wide Receiver | Jerry Jeudy | DaeSean Hamilton | Kendall Hinton |
| Wide Receiver | Courtland Sutton | Tim Patrick | Trinity Benson |
| Wide Receiver | KJ Hamler | Diontae Spencer | Tyrie Cleveland |
| Running Back | Melvin Gordon III | Royce Freeman | LeVante Bellamy |
| Tight End | Noah Fant | Austin Fort | Andrew Beck |
| Quarterback | Drew Lock | Jeff Driskel | Brett Rypien |
| Defense | |||
| Position | |||
| Left Defensive End | DeShawn Williams | Shamar Stephen | Isaiah Mack |
| Nose Tackle | Mike Purcell | McTelvin Agim | Deyon Sizer |
| Right Defensive End | Shelby Harris | Dre'Mont Jones | Jonathan Harris |
| Left Outside Linebacker | Bradley Chubb | Malik Reed | Josh Watson |
| Left Inside Linebacker | A.J. Johnson | ||
| Right Outside Linebacker | Von Miller | Derrek Tuszka | |
| Right Inside Linebacker | Josey Jewell | Jacob Bobenmoyer | Natrez Patrick |
| Left Cornerback | Michael Ojemudia | Bryce Callahan | Nate Hairston |
| Right Cornerback | Kyle Fuller | Ronald Darby | Parnell Motley |
| Strong Safety | Kareem Jackson | Trey Marshall | |
| Free Safety | Justin Simmons | P.J. Locke | Chris Cooper |
| Special Teams | |||
| Position | |||
| Kicker | Brandon McManus | ||
| Kick-Offs | Brandon McManus | ||
| Punter | Sam Martin | ||
| Kick Returner | Tyrie Cleveland | KJ Hamler | |
| Punt Returner | KJ Hamler | ||
| Holder | Sam Martin | ||
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